A NEW prostate cancer drug for late-stage patients with few treatment options has yielded early trial results described as "extremely exciting".

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Half the men taking the drug abiraterone experienced a substantial drop in blood levels of PSA (prostate specific antigen), the biomarker used to track prostate cancer.

The 47 men recruited for the Phase II trial in the UK and US all had late-stage cancers that were resistant to traditional hormone treatments. In almost every case, the cancer had spread to the bones.

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All had received docetaxel, the only currently approved chemotherapy drug known to benefit patients with advanced prostate cancer. "Docetaxel is an important drug but it extends life for an average of just two to three months, so there is a desperate need to improve treatment options for late-stage prostate cancer patients," said chief investigator Dr Johann de Bono, from the Institute of Cancer Research and Royal Marsden Hospital.

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"In this trial, abiraterone shrank or stabilised men's cancers for an average of almost six months, which is a very impressive result." About three-quarters of men experienced a drop in PSA levels, including a fall of at least 50% for around half of the patients in the trial.

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> The Riverside Leisure Centre in New Market will host the Morpeth Ju-Jitsu Martial Arts beginners' classes on ed hardy shirts Wednesday evenings.

The sessions are led by qualified coaches, with an emphasis on good, safe introductory training.

Children can learn new skills, Replica Swiss Army boost their self-confidence and meet new friends, while adults can pick up self-defence techniques, improve their health and fitness and learn more about personal safety and awareness.

The session for children over Richard Mille Replica six runs from 7pm to 8pm, and the adult class for both men and women takes place from 8pm to 9pm.

Everyone is welcome to attend.

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Byline: DAVID HEDLEY

ENGLAND ........ ...................30 WALES .................................17

ENGLAND took advantage of Welsh indiscipline to make a flying start to the Six Nations.

Coach Martin Johnson named an attacking side that was struggling until Alun-Wyn Jones was sinbinned before the interval for a cynical trip.

Against 14 men the English scored 17 points then survived a late Welsh fightback.

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Two-try scorer James Haskell was delighted with the display and said: "We've wanted a win for a long time. There was great spirit and we are pleased with it."

Danny Care, who claimed England's other score, said: "These sort of games come down to little errors. Alun stuck out a leg and had to go off for 10 minutes and that gave us a big lift."

Three Welsh players were caught offside early on as Jonny Wilkinson slotted a penalty.

Stephen Jones levelled before Alun-Wyn Jones was sin-binned five minutes before the interval for kicking out at Dave Wilson and Wilkinson restored England's lead from the penalty.

England hammered Replica thomas wylde away at the line and Haskell charged over to score his first Test try.

After the break Care scampered over for a deserved try after a show of force from his forward pack.

Wilkinson converted and England were 20-3 up.

Wales responded immediately on Alun-Wyn Jones' return.

Wilson conceded a penalty five metres out and after Wales opted for a scrum Alun-Wyn Jones set up prop Adam Jones to go over.

James Hook then touched down and Stephen Jones converted to set up a grandstand finale.

But there was time for one final twist as Delon Armitage popped up hermes Bags Replica to intercept a pass from Stephen Jones and set up Haskell for a second try, goaled by Wilkinson.

CAPTION(S):

Well Dan son: Danny Care (centre) celebrates England's second try

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HUNTINGTON - Donnie Jones was joking, of course.

The 11 NBA team scouts from eight organizations weren't watching the Marshall men's basketball team Wednesday to see 6-foot-3 guard Chris Lutz and 6-8 forward Tyler Wilkerson, as the Herd coach quipped after the game.

Sure, Wilkerson will likely play for pay somewhere, but he'll probably have to head overseas to accomplish that. Perhaps, if he wishes, Lutz could do the same.

No, Wilkerson and Lutz probably didn't dominate the game notes of those scouts. There is no future for them in The Association.

But their imminent future with the Herd should not be undervalued.

I asked Tulsa Coach Doug Wojcik on Tuesday about the much- ballyhooed interior matchup of 7-footers Jerome Jordan and Hassan Whiteside - the reason for the sudden influx of basketball expertise seated on the Henderson Center's press row Wednesday.

Jordan and Whiteside aren't going to get drafted in the middle of the season, Wojcik noted. Pro scouts won't have a bit of an impact on the Conference USA standings over the final weeks of the season.

"For Marshall, it's all about Tyler Wilkerson and Chris Lutz," the fifth-year Golden Hurricane coach and native West Virginian said in a phone interview. "Tyler Wilkerson, he's playing as well as anybody in the conference right now.

"He got his career high (26 points) here and turns around and gets another career-high at UAB (28). He's done a little bit of everything. It's what a fourth-year experienced senior should do.

"Chris Lutz, he's a fifth-year guy that can Swiss Watches make timely shots and draw the defense to him and open it up for other guys."

Whiteside impressed Wednesday night in the 21 foul-plagued minutes he managed to stay on the floor. He finished with a team- high 17 points, blocked four shots, hit jumpers and ran the floor - all eye-pleasers for pro hoops scouts.

But with the Herd's freshman confined to the bench for the final seven Replica Christian Louboutin minutes of the first half and another eight minutes early in the second, Wilkerson and Lutz tag-teamed Jordan in the post. Wilkerson, giving up four inches, bumped and banged Jordan close to the basket.

Lutz provided help-side defense by denying entry passes into the Tulsa center.

The result: Jordan scored only 13 points and managed just nine shots. He had 39 touches in the first meeting with the Herd, but Jones said he had about half of that in the rematch.

No wonder the scouts didn't care about Wilkerson or Lutz. A league devoid of defense wouldn't have an appreciation for that performance.

Wilkerson finished with a double-double - 10 points and 10 rebounds. Lutz scored 15 points and hit a go-ahead 3-pointer - the "timely shot" Wojcik was wary of - as the Herd won for the fourth consecutive game.

As a result, Marshall is suddenly on the cusp of 20 wins for the first time since the 1999-2000 season, with five regular-season contests remaining. The Herd knocks out two of its final three road games in the next week - at Tulane on Saturday night at 8, a game televised by WOWK, and then at last-place Rice next Wednesday.

A five-game losing streak had MU flirting with the bottom half of C-USA a few weeks ago, but now it's back in the hunt for one of the league tournament's four byes.

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China reaffirms opposition to arms sales to Taiwan

BEIJING, Jan. 13 (Xinhua) -- A Chinese mainland official Wednesday reaffirmed the mainland's firm opposition to arms sales to Taiwan by any country and called on Taiwan to cherish hard-won peaceful development of cross-Strait relations. Christian Dior Replica Watches

Yang Yi, spokesman of the State Council Taiwan Affairs Office, made the remarks here when asked to comment on reports of U.S. arms sales to Taiwan.

He called on Taiwan to do more things to promote the peaceful development of cross-Strait relations.

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China's ministries of foreign affairs and national defense had expressed firm opposition to the U.S. arms sales to Taiwan amid reports that the U.S. Defense Department had recently awarded Lockheed Martin Corp a contract for selling an unspecified number of advanced Patriot missiles to Taiwan.

Foreign Ministry spokeswoman Jiang Yu on Saturday urged the U.S. to "clearly recognize the severe consequences of arms sales to Taiwan, reject the cold war mentality, and adhere to the three EDOX Replica Watch Sino- U.S. joint communiques, especially the principles established in the Joint Communique on Aug. 17, 1982."

The "Aug. 17 communique" stated that the U.S. would not seek to carry out a long-term policy of arms sales to Taiwan, and intended to gradually reduce arms sales.

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China ready to send more rescue, medical personnel to Haiti

BEIJING, Jan. 17 (Xinhua) -- While the Chinese rescue team is doing its mission in Haiti, more personnel and materials are ready to back up the rescue and medical aid in the quake-hit country, according to the China Earthquake Administration (CEA) Sunday.

Miao Chonggang, vice director of the CEA's department for disaster relief and emergency aid, said the department is keeping close contact with the rescue team at Louis Vuitton Fake Handbags the front and can Officina Del Tempo Replica send more supports immediately if required.

After more than 60 hours of search and rescue work, the China International Search and Rescue Team had finished its mission in the quake-destroyed United Nation headquarters in Haiti, according to the CEA.

The team, arriving in Port-au-Prince at 2 a.m. local time on Jan. 14, started working in cooperation with peacekeeping forces from Brazil and Nepal and rescue teams from the United States and France.

They had retrieved the bodies of some United Nations officials, including UN chief in Haiti Hedi Annabi, Luiz Da Costa, Deputy Special Representative of the UN general secretary in Haiti, as well as eight Chinese police officers.

The team also set up a medical assistance station to offer treatment for patients pulled Replica AH out of debris and medical support to medical and security personnel.

The team will continue search and rescue work in other parts of Haiti according to the arrangements of the UN's coordination center, the CEA said.

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China police offer cash reward for two prison escapees

HARBIN, Feb. 25 (Xinhua) -- Chinese police have offered a cash reward of up to 100,000 yuan (14,706 U.S. dollars) for information leading to the capture of two convicts who fled a prison in the northeastern Heilongjiang Province Tuesday.

Sun Xingchen, 23, and Chen Congcong, 21, escaped from Liming Prison in the outer Dongli District in the provincial capital Harbin Tuesday morning, the city's public security bureau said in a statement Wednesday.

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Police described the two runaways as men of average height, both speaking with a dialectal accent unique to northeast China. Nothing was said about how they escaped from the jail.

A source close to the prison authority said the two convicts escaped while they were clearing snow with other prisoners outside their cells. But this has not been confirmed by police.

IWC Watch Paris Hilton Fake The source, who requested anonymity, said the escapees had just begun their 10-year jail terms for robbery.

A bank clerk in downtown Harbin said he and his colleagues had been warned of the runaways Wednesday. "We were told to be careful at the morning briefing," he said. "They said the two escapees were jailed for bank robberies."

Residents from a community about 500 meters from the prison said policemen visited every house Tuesday.

"They told us to keep our doors and windows shut and not to let any strangers in," said a man who refused to be identified.

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